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Key Roles of AXL and MER Receptor Tyrosine Kinases in Resistance to Multiple Anticancer Therapies

A major challenge in anticancer treatment is the pre-existence or emergence of resistance to therapy. AXL and MER are two members of the TAM (TYRO3-AXL-MER) family of receptor tyrosine kinases, which, when activated, can regulate tumor cell survival, proliferation, migration and invasion, angiogenes...

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Detalhes bibliográficos
Publicado no:Curr Oncol Rep
Main Authors: Schoumacher, Marie, Burbridge, Mike
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5332501/
https://ncbi.nlm.nih.gov/pubmed/28251492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11912-017-0579-4
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