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Role of TRPA1 in Acute Cardiopulmonary Toxicity of Inhaled Acrolein

Acrolein is a highly toxic, volatile, unsaturated aldehyde generated during incomplete combustion as in tobacco smoke and indoor fires. Because the transient receptor potential ankyrin 1 (TRPA1) channel mediates tobacco smoke-induced lung injury, we assessed its role in high-level acrolein-induced t...

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Detalhes bibliográficos
Publicado no:Toxicol Appl Pharmacol
Main Authors: Conklin, Daniel J., Haberzettl, Petra, Jagatheesan, Ganapathy, Kong, Maiying, Hoyle, Gary W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5332481/
https://ncbi.nlm.nih.gov/pubmed/27592100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2016.08.028
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