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A dangerous liaison: Leptin and sPLA2-IIA join forces to induce proliferation and migration of astrocytoma cells

Glioblastoma, the most aggressive type of primary brain tumour, shows worse prognosis linked to diabetes or obesity persistence. These pathologies are chronic inflammatory conditions characterized by altered profiles of inflammatory mediators, including leptin and secreted phospholipase A(2)-IIA (sP...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Martín, Rubén, Cordova, Claudia, Gutiérrez, Beatriz, Hernández, Marita, Nieto, María L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331986/
https://ncbi.nlm.nih.gov/pubmed/28249041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170675
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