A dangerous liaison: Leptin and sPLA2-IIA join forces to induce proliferation and migration of astrocytoma cells

Glioblastoma, the most aggressive type of primary brain tumour, shows worse prognosis linked to diabetes or obesity persistence. These pathologies are chronic inflammatory conditions characterized by altered profiles of inflammatory mediators, including leptin and secreted phospholipase A(2)-IIA (sP...

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Publicat a:PLoS One
Autors principals: Martín, Rubén, Cordova, Claudia, Gutiérrez, Beatriz, Hernández, Marita, Nieto, María L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331986/
https://ncbi.nlm.nih.gov/pubmed/28249041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170675
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