Characterization of Hepatitis C Virus (HCV) Envelope Diversification from Acute to Chronic Infection within a Sexually Transmitted HCV Cluster by Using Single-Molecule, Real-Time Sequencing

In contrast to other available next-generation sequencing platforms, PacBio single-molecule, real-time (SMRT) sequencing has the advantage of generating long reads albeit with a relatively higher error rate in unprocessed data. Using this platform, we longitudinally sampled and sequenced the hepatit...

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Veröffentlicht in:J Virol
Hauptverfasser: Ho, Cynthia K. Y., Raghwani, Jayna, Koekkoek, Sylvie, Liang, Richard H., Van der Meer, Jan T. M., Van Der Valk, Marc, De Jong, Menno, Pybus, Oliver G., Schinkel, Janke, Molenkamp, Richard
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Genetic Diversity and Evolution
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331808/
https://ncbi.nlm.nih.gov/pubmed/28077634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02262-16
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