Characterization of Hepatitis C Virus (HCV) Envelope Diversification from Acute to Chronic Infection within a Sexually Transmitted HCV Cluster by Using Single-Molecule, Real-Time Sequencing

In contrast to other available next-generation sequencing platforms, PacBio single-molecule, real-time (SMRT) sequencing has the advantage of generating long reads albeit with a relatively higher error rate in unprocessed data. Using this platform, we longitudinally sampled and sequenced the hepatit...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Ho, Cynthia K. Y., Raghwani, Jayna, Koekkoek, Sylvie, Liang, Richard H., Van der Meer, Jan T. M., Van Der Valk, Marc, De Jong, Menno, Pybus, Oliver G., Schinkel, Janke, Molenkamp, Richard
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
Materias:
Genetic Diversity and Evolution
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331808/
https://ncbi.nlm.nih.gov/pubmed/28077634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02262-16
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