BRD4 Couples NF-κB/RelA with Airway Inflammation and the IRF-RIG-I Amplification Loop in Respiratory Syncytial Virus Infection

The airway mucosa expresses protective interferon (IFN) and inflammatory cytokines in response to respiratory syncytial virus (RSV) infection. In this study, we examine the role of bromodomain containing 4 (BRD4) in mediating this innate immune response in human small airway epithelial cells. We obs...

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Vydáno v:J Virol
Hlavní autoři: Tian, Bing, Yang, Jun, Zhao, Yingxin, Ivanciuc, Teodora, Sun, Hong, Garofalo, Roberto P., Brasier, Allan R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Cellular Response to Infection
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331805/
https://ncbi.nlm.nih.gov/pubmed/28077651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00007-17
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