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Adenovirus Modulates Toll-Like Receptor 4 Signaling by Reprogramming ORP1L-VAP Protein Contacts for Cholesterol Transport from Endosomes to the Endoplasmic Reticulum

Human adenoviruses (Ads) generally cause mild self-limiting infections but can lead to serious disease and even be fatal in high-risk individuals, underscoring the importance of understanding how the virus counteracts host defense mechanisms. This study had two goals. First, we wished to determine t...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Cianciola, Nicholas L., Chung, Stacey, Manor, Danny, Carlin, Cathleen R.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331795/
https://ncbi.nlm.nih.gov/pubmed/28077646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01904-16
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