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STARD3 mediates endoplasmic reticulum‐to‐endosome cholesterol transport at membrane contact sites

StAR‐related lipid transfer domain‐3 (STARD3) is a sterol‐binding protein that creates endoplasmic reticulum (ER)–endosome contact sites. How this protein, at the crossroad between sterol uptake and synthesis pathways, impacts the intracellular distribution of this lipid was ill‐defined. Here, by us...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Wilhelm, Léa P, Wendling, Corinne, Védie, Benoît, Kobayashi, Toshihide, Chenard, Marie‐Pierre, Tomasetto, Catherine, Drin, Guillaume, Alpy, Fabien
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430228/
https://ncbi.nlm.nih.gov/pubmed/28377464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695917
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