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S-Allylmercaptocysteine Attenuates Cisplatin-Induced Nephrotoxicity through Suppression of Apoptosis, Oxidative Stress, and Inflammation

Cisplatin is a potent chemotherapeutic agent, but its clinical usage is limited by nephrotoxicity. S-allylmercaptocysteine (SAMC), one of the water-soluble organosulfur garlic derivatives, has antioxidant and anti-inflammatory properties and plays an important role in protecting cells from apoptosis...

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Vydáno v:Nutrients
Hlavní autoři: Zhu, Xiaosong, Jiang, Xiaoyan, Li, Ang, Zhao, Zhongxi, Li, Siying
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331597/
https://ncbi.nlm.nih.gov/pubmed/28230744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu9020166
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