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CADEE: Computer-Aided Directed Evolution of Enzymes

The tremendous interest in enzymes as biocatalysts has led to extensive work in enzyme engineering, as well as associated methodology development. Here, a new framework for computer-aided directed evolution of enzymes (CADEE) is presented which allows a drastic reduction in the time necessary to pre...

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Pubblicato in:IUCrJ
Autori principali: Amrein, Beat Anton, Steffen-Munsberg, Fabian, Szeler, Ireneusz, Purg, Miha, Kulkarni, Yashraj, Kamerlin, Shina Caroline Lynn
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331465/
https://ncbi.nlm.nih.gov/pubmed/28250941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2052252516018017
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