The Combination of MBP and BCG-Induced Dendritic Cell Maturation through TLR2/TLR4 Promotes Th1 Activation In Vitro and Vivo

To explore whether TLR2/TLR4 could be involved in the maturation of dendritic cells and polarization of CD4(+) T cells induced by dendritic cells stimulated with MBP and BCG, in vitro and in vivo experiments using TLR2(−/−) or TLR4(−/−) mice were employed. MBP and BCG elevated CD80, CD86 and MHC cla...

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Udgivet i:Mediators Inflamm
Main Authors: Jiang, LiNa, Liu, GuoMu, Ni, WeiHua, Zhang, NanNan, Jie, Jing, Xie, Fei, Tai, GuiXiang
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331320/
https://ncbi.nlm.nih.gov/pubmed/28293065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/1953680
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