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Continuous-flow synthesis of highly functionalized imidazo-oxadiazoles facilitated by microfluidic extraction
A versatile continuous-flow synthesis of highly functionalized 1,2,4-oxadiazoles starting from carboxylic acids is reported. This process was applied to the multistep synthesis of imidazo[1,2-a]pyridin-2-yl-1,2,4-oxadiazoles, using a three reactor, multistep continuous-flow system without isolation...
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| Publicado no: | Beilstein J Org Chem |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Beilstein-Institut
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5331298/ https://ncbi.nlm.nih.gov/pubmed/28326132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.13.26 |
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