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MARK4 inhibits Hippo signaling to promote proliferation and migration of breast cancer cells

The Hippo pathway is a critical regulator of tissue size, and aberrations in pathway regulation lead to cancer. MST1/2 and LATS1/2 kinases comprise the core of the pathway that, in association with adaptor proteins SAV and MOB, functions in a sequential manner to phosphorylate and inhibit the transc...

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Podrobná bibliografie
Vydáno v:EMBO Rep
Hlavní autoři: Heidary Arash, Emad, Shiban, Ahmed, Song, Siyuan, Attisano, Liliana
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331264/
https://ncbi.nlm.nih.gov/pubmed/28183853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642455
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