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Restricted access: spatial sequestration of damaged proteins during stress and aging
The accumulation of damaged and aggregated proteins is a hallmark of aging and increased proteotoxic stress. To limit the toxicity of damaged and aggregated proteins and to ensure that the damage is not inherited by succeeding cell generations, a system of spatial quality control operates to sequest...
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| Publicado no: | EMBO Rep |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5331209/ https://ncbi.nlm.nih.gov/pubmed/28193623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643458 |
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