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Restricted access: spatial sequestration of damaged proteins during stress and aging

The accumulation of damaged and aggregated proteins is a hallmark of aging and increased proteotoxic stress. To limit the toxicity of damaged and aggregated proteins and to ensure that the damage is not inherited by succeeding cell generations, a system of spatial quality control operates to sequest...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EMBO Rep
Egile Nagusiak: Hill, Sandra Malmgren, Hanzén, Sarah, Nyström, Thomas
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331209/
https://ncbi.nlm.nih.gov/pubmed/28193623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643458
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