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Cabozantinib: an Active Novel Multikinase Inhibitor in Renal Cell Carcinoma
Clear cell renal cell carcinoma (RCC) is characterized by inactivation of the von Hippel-Lindau (VHL) tumor suppressor gene. VHL loss drives tumor angiogenesis and accounts for the clinical activity of VEGF receptor (VEGFR) tyrosine kinase inhibitors (TKIs), the first-line standard of care for advan...
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| Pubblicato in: | Curr Oncol Rep |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer US
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5331092/ https://ncbi.nlm.nih.gov/pubmed/28247252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11912-017-0566-9 |
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