A High-Capacity Adenoviral Hybrid Vector System Utilizing the Hyperactive Sleeping Beauty Transposase SB100X for Enhanced Integration

For efficient delivery of required genetic elements we utilized high-capacity adenoviral vectors in the past allowing high transgene capacities of up to 36 kb. Previously we explored the hyperactive Sleeping Beauty (SB) transposase (HSB5) for somatic integration from the high-capacity adenoviral vec...

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Bibliografiske detaljer
Udgivet i:Mol Ther Nucleic Acids
Main Authors: Boehme, Philip, Zhang, Wenli, Solanki, Manish, Ehrke-Schulz, Eric, Ehrhardt, Anja
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330939/
https://ncbi.nlm.nih.gov/pubmed/27434682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.44
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