Cloning and Large-Scale Production of High-Capacity Adenoviral Vectors Based on the Human Adenovirus Type 5

High-capacity adenoviral vectors (HCAdV) devoid of all viral coding sequences represent one of the most advanced gene delivery vectors due to their high packaging capacity (up to 35 kb), low immunogenicity and low toxicity. However, for many laboratories the use of HCAdV is hampered by the complicat...

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書目詳細資料
發表在:J Vis Exp
Main Authors: Ehrke-Schulz, Eric, Zhang, Wenli, Schiwon, Maren, Bergmann, Thorsten, Solanki, Manish, Liu, Jing, Boehme, Philip, Leitner, Theo, Ehrhardt, Anja
格式: Artigo
語言:Inglês
出版: MyJove Corporation 2016
主題:
Bioengineering
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781703/
https://ncbi.nlm.nih.gov/pubmed/26863087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52894
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