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Cloning and Large-Scale Production of High-Capacity Adenoviral Vectors Based on the Human Adenovirus Type 5

High-capacity adenoviral vectors (HCAdV) devoid of all viral coding sequences represent one of the most advanced gene delivery vectors due to their high packaging capacity (up to 35 kb), low immunogenicity and low toxicity. However, for many laboratories the use of HCAdV is hampered by the complicat...

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Publicat a:J Vis Exp
Autors principals: Ehrke-Schulz, Eric, Zhang, Wenli, Schiwon, Maren, Bergmann, Thorsten, Solanki, Manish, Liu, Jing, Boehme, Philip, Leitner, Theo, Ehrhardt, Anja
Format: Artigo
Idioma:Inglês
Publicat: MyJove Corporation 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781703/
https://ncbi.nlm.nih.gov/pubmed/26863087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52894
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