Cloning and Large-Scale Production of High-Capacity Adenoviral Vectors Based on the Human Adenovirus Type 5

High-capacity adenoviral vectors (HCAdV) devoid of all viral coding sequences represent one of the most advanced gene delivery vectors due to their high packaging capacity (up to 35 kb), low immunogenicity and low toxicity. However, for many laboratories the use of HCAdV is hampered by the complicat...

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Vydáno v:J Vis Exp
Hlavní autoři: Ehrke-Schulz, Eric, Zhang, Wenli, Schiwon, Maren, Bergmann, Thorsten, Solanki, Manish, Liu, Jing, Boehme, Philip, Leitner, Theo, Ehrhardt, Anja
Médium: Artigo
Jazyk:Inglês
Vydáno: MyJove Corporation 2016
Témata:
Bioengineering
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781703/
https://ncbi.nlm.nih.gov/pubmed/26863087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52894
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