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Cloning and Large-Scale Production of High-Capacity Adenoviral Vectors Based on the Human Adenovirus Type 5

High-capacity adenoviral vectors (HCAdV) devoid of all viral coding sequences represent one of the most advanced gene delivery vectors due to their high packaging capacity (up to 35 kb), low immunogenicity and low toxicity. However, for many laboratories the use of HCAdV is hampered by the complicat...

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Bibliografski detalji
Izdano u:J Vis Exp
Glavni autori: Ehrke-Schulz, Eric, Zhang, Wenli, Schiwon, Maren, Bergmann, Thorsten, Solanki, Manish, Liu, Jing, Boehme, Philip, Leitner, Theo, Ehrhardt, Anja
Format: Artigo
Jezik:Inglês
Izdano: MyJove Corporation 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781703/
https://ncbi.nlm.nih.gov/pubmed/26863087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52894
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