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Paradoxical bleeding and thrombotic episodes of dysprothrombinemia due to a homozygous Arg382His mutation
We have characterized the pathogenic basis of dysprothrombinemia in a patient exhibiting paradoxical bleeding and thrombotic defects during pregnancy and postpartum. Genetic analysis revealed that the proband is homozygous for the prothrombin Arg382His mutation, possessing only ~1% clotting activity...
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| 發表在: | Thromb Haemost |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5330935/ https://ncbi.nlm.nih.gov/pubmed/27975099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH16-10-0750 |
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