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Paradoxical bleeding and thrombotic episodes of dysprothrombinemia due to a homozygous Arg382His mutation

We have characterized the pathogenic basis of dysprothrombinemia in a patient exhibiting paradoxical bleeding and thrombotic defects during pregnancy and postpartum. Genetic analysis revealed that the proband is homozygous for the prothrombin Arg382His mutation, possessing only ~1% clotting activity...

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書目詳細資料
發表在:Thromb Haemost
Main Authors: Ding, Qiulan, Yang, Likui, Zhao, Xiaoqing, Wu, Wenman, Wang, Xuefeng, Rezaie, Alireza R.
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330935/
https://ncbi.nlm.nih.gov/pubmed/27975099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH16-10-0750
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