Characterizing cell subsets in heterogeneous tissues using marker enrichment modeling

Learning cell identity from single-cell data presently relies on human experts. Here, we present Marker Enrichment Modeling (MEM), an algorithm that objectively describes cells by quantifying contextual feature enrichment and reporting a human and machine-readable text label. MEM outperformed tradit...

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Vydáno v:Nat Methods
Hlavní autoři: Diggins, K. E., Greenplate, A. R., Leelatian, N., Wogsland, C. E., Irish, J. M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330853/
https://ncbi.nlm.nih.gov/pubmed/28135256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4149
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