Limited naturally occurring escape in broadly neutralizing antibody epitopes in hepatitis C glycoprotein E2 and constrained sequence usage in acute infection

Broadly neutralizing antibodies have been associated with spontaneous clearance of the hepatitis C infection as well as viral persistence by immune escape. Further study of neutralizing antibody epitopes is needed to unravel pathways of resistance to virus neutralization, and to identify conserved r...

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Publicado en:Infect Genet Evol
Main Authors: Rodrigo, Chaturaka, Walker, Melanie R., Leung, Preston, Eltahla, Auda A., Grebely, Jason, Dore, Gregory J., Applegate, Tanya, Page, Kimberly, Dwivedi, Sunita, Bruneau, Julie, Morris, Meghan D., Cox, Andrea L., Osburn, William, Kim, Arthur Y., Schinkel, Janke, Shoukry, Naglaa H., Lauer, Georg M., Maher, Lisa, Hellard, Margaret, Prins, Maria, Luciani, Fabio, Lloyd, Andrew R., Bull, Rowena A.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330849/
https://ncbi.nlm.nih.gov/pubmed/28065804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.meegid.2017.01.006
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