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DREADDing proglucagon neurons: a fresh look at metabolic regulation by the brain
Glucagon-like peptide 1 receptor (GLP-1R) signaling in the CNS has been linked to reduced food intake, lower body weight, improved glucose homeostasis, and activation of CNS stress axes. GLP-1 is produced by cells that express proglucagon (GCG); however, the stimuli that activate GCG(+) neurons are...
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| Publicado no: | J Clin Invest |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5330747/ https://ncbi.nlm.nih.gov/pubmed/28218623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI92845 |
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