An Oncogenic ALK Fusion and an RRAS Mutation in KRAS Mutation‐Negative Pancreatic Ductal Adenocarcinoma

PURPOSE. Oncogenic mutations in the KRAS gene are a well‐known driver event, occurring in >95% of pancreatic cancers. The objective of this study was to identify driver oncogene aberrations in pancreatic cancers without the KRAS mutation. METHODS. Whole‐exome and transcriptome sequencing was perf...

Full description

Saved in:
Bibliographic Details
Published in:Oncologist
Main Authors: Shimada, Yoko, Kohno, Takashi, Ueno, Hideki, Ino, Yoshinori, Hayashi, Hideyuki, Nakaoku, Takashi, Sakamoto, Yasunari, Kondo, Shunsuke, Morizane, Chigusa, Shimada, Kazuaki, Okusaka, Takuji, Hiraoka, Nobuyoshi
Format: Artigo
Language:Inglês
Published: AlphaMed Press 2017
Subjects:
Gastrointestinal Cancer
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330701/
https://ncbi.nlm.nih.gov/pubmed/28167572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2016-0194
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items