Myristoylation of an inhibitory GTP-binding protein alpha subunit is essential for its membrane attachment.

We transfected COS cells with cDNAs for the alpha subunits of stimulatory and inhibitory GTP-binding proteins, alpha s and alpha i1, respectively, and immunoprecipitated the metabolically labeled products with specific peptide antibodies. Cells were separated into particulate and soluble fractions b...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Jones, T L, Simonds, W F, Merendino, J J, Brann, M R, Spiegel, A M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53306/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2105488/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.2.568
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