Myristoylation of an inhibitory GTP-binding protein alpha subunit is essential for its membrane attachment.

We transfected COS cells with cDNAs for the alpha subunits of stimulatory and inhibitory GTP-binding proteins, alpha s and alpha i1, respectively, and immunoprecipitated the metabolically labeled products with specific peptide antibodies. Cells were separated into particulate and soluble fractions b...

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Bibliographische Detailangaben
Hauptverfasser: Jones, T L, Simonds, W F, Merendino, J J, Brann, M R, Spiegel, A M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1990
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC53306/
https://ncbi.nlm.nih.gov/pubmed/2105488
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