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Doxorubicin-induced oxidative stress: The protective effect of nicorandil on HL-1 cardiomyocytes

The primary cardiotoxic action of doxorubicin when used as antitumor drug is attributed to the generation of reactive oxygen species (ROS) therefore effective cardioprotection therapies are needed. In this sense, the antianginal drug nicorandil has been shown to be effective in cardioprotection from...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Asensio-López, Mari C., Soler, Fernando, Pascual-Figal, Domingo, Fernández-Belda, Francisco, Lax, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330507/
https://ncbi.nlm.nih.gov/pubmed/28245258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172803
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