Protective effect of guggulsterone against cardiomyocyte injury induced by doxorubicin in vitro

BACKGROUND: Doxorubicin (DOX) is an effective antineoplastic drug; however, clinical use of DOX is limited by its dose-dependent cardiotoxicity. It is well known that reactive oxygen species (ROS) play a vital role in the pathological process of DOX-induced cardiotoxicity. For this study, we evaluat...

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Main Authors: Wang, Wen-Ching, Uen, Yih-Huei, Chang, Ming-Long, Cheah, Khoot-Peng, Li, Joe-Sharg, Yu, Wen-Yu, Lee, Kock-Chee, Choy, Cheuk-Sing, Hu, Chien-Ming
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493356/
https://ncbi.nlm.nih.gov/pubmed/22920231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6882-12-138
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