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The epigenetic regulation of Dicer and microRNA biogenesis by Panobinostat

microRNAs (miRs) are small noncoding RNAs that regulate/fine tune many cellular protein networks by targeting mRNAs for either degradation or translational inhibition. Dicer, a type III endoribonuclease, is a critical component in miR biogenesis and is required for mature microRNA production. Abnorm...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Hoffend, Nicholas C., Magner, William J., Tomasi, Thomas B.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330440/
https://ncbi.nlm.nih.gov/pubmed/27935420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2016.1267886
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