Activation of the pp60c-src protein kinase is an early event in colonic carcinogenesis.
Colonic neoplasia provides an opportunity to study tumor progression because most carcinomas arise from adenomas (polyps), which, in turn, arise from normal epithelia. The malignant potential of adenomas varies with size, histology, and degree of dysplasia. Polyps that are less than 2 cm with villou...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1990
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53304/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2105487/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.2.558 |
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