Heat-shock protein hsp90 governs the activity of pp60v-src kinase.
During or immediately after synthesis in vertebrate cells, the oncogenic protein-tyrosine kinase pp60v-src associates with the approximately 90-kDa heat-shock protein (hsp90). In this complex, pp60v-src is not functional as a kinase. When pp60v-src is subsequently found inserted into the plasma memb...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1993
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47078/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7688470/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.15.7074 |
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