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Heat-shock protein hsp90 governs the activity of pp60v-src kinase.

During or immediately after synthesis in vertebrate cells, the oncogenic protein-tyrosine kinase pp60v-src associates with the approximately 90-kDa heat-shock protein (hsp90). In this complex, pp60v-src is not functional as a kinase. When pp60v-src is subsequently found inserted into the plasma memb...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Xu, Y, Lindquist, S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1993
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47078/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7688470/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.15.7074
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