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Torsional Steering as Friend and Foe: Development of a Synthetic Route to the Briarane Diterpenoid Stereotetrad

Two synthetic routes to the briarane stereotetrad have been investigated. The first route employed a boron aldol reaction to establish the stereogenic all-carbon quaternary carbon (C1). In this case, it was found that torsional steering in the transition state led to the formation of the undesired c...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Moon, Nicholas G., Harned, Andrew M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330299/
https://ncbi.nlm.nih.gov/pubmed/28169385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7ob00124j
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