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Flagellin/TLR5 responses in epithelia reveal intertwined activation of inflammatory and apoptotic pathways

Flagellin, the primary structural component of bacterial flagella, is recognized by Toll-like receptor 5 (TLR5) present on the basolateral surface of intestinal epithelial cells. Utilizing biochemical assays of proinflammatory signaling pathways and mRNA expression profiling, we found that purified...

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Détails bibliographiques
Publié dans:Am J Physiol Gastrointest Liver Physiol
Auteurs principaux: Zeng, Hui, Wu, Huixia, Sloane, Valerie, Jones, Rheinallt, Yu, Yimin, Lin, Patricia, Gewirtz, Andrew T., Neish, Andrew S.
Format: Artigo
Langue:Inglês
Publié: 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330286/
https://ncbi.nlm.nih.gov/pubmed/16179598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00273.2005
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