Mitochondrial DNA has a pro-inflammatory role in AMD

Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in the elderly of industrialized nations, and there is increasing evidence to support a role for chronic inflammation in its pathogenesis. Mitochondrial DNA (mtDNA) has been recently reported to be pro-inflammatory...

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Pubblicato in:Biochim Biophys Acta
Autori principali: Dib, Bernard, Lin, Haijiang, Maidana, Daniel E., Tian, Bo, Miller, John B., Bouzika, Peggy, Miller, Joan W., Vavvas, Demetrios G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330253/
https://ncbi.nlm.nih.gov/pubmed/26305120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2015.08.012
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