Pharmacokinetic interactions between glimepiride and rosuvastatin in healthy Korean subjects: does the SLCO1B1 or CYP2C9 genetic polymorphism affect these drug interactions?

To improve cardiovascular outcomes, dyslipidemia in patients with diabetes needs to be treated. Thus, these patients are likely to take glimepiride and rosuvastatin concomitantly. Therefore, this study aimed to evaluate the pharmacokinetic (PK) interactions between these two drugs in healthy males a...

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Foilsithe in:Drug Des Devel Ther
Main Authors: Kim, Choon Ok, Oh, Eun Sil, Kim, Hohyun, Park, Min Soo
Formáid: Artigo
Teanga:Inglês
Foilsithe: Dove Medical Press 2017
Ábhair:
Original Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330189/
https://ncbi.nlm.nih.gov/pubmed/28260863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S129586
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