Pharmacokinetic interactions between glimepiride and rosuvastatin in healthy Korean subjects: does the SLCO1B1 or CYP2C9 genetic polymorphism affect these drug interactions?

To improve cardiovascular outcomes, dyslipidemia in patients with diabetes needs to be treated. Thus, these patients are likely to take glimepiride and rosuvastatin concomitantly. Therefore, this study aimed to evaluate the pharmacokinetic (PK) interactions between these two drugs in healthy males a...

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Veröffentlicht in:Drug Des Devel Ther
Hauptverfasser: Kim, Choon Ok, Oh, Eun Sil, Kim, Hohyun, Park, Min Soo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2017
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330189/
https://ncbi.nlm.nih.gov/pubmed/28260863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S129586
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