Effect of HIV-1 envelope cytoplasmic tail on adenovirus primed virus encoded virus-like particle immunizations

The low number of envelope (Env) spikes presented on native HIV-1 particles is a major impediment for HIV-1 prophylactic vaccine development. We designed virus-like particle encoding adenoviral vectors utilizing SIVmac239 Gag as an anchor for full length and truncated HIV-1 M consensus Env. Truncate...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Andersson, Anne-Marie C., Ragonnaud, Emeline, Seaton, Kelly E., Sawant, Sheetal, Folgori, Antonella, Colloca, Stefano, Labranche, Celia, Montefiori, David C., Tomaras, Georgia D., Holst, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330181/
https://ncbi.nlm.nih.gov/pubmed/27633665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2016.08.089
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