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WNK kinases in development and disease

WNK (With-No-Lysine (K)) kinases are serine-threonine kinases characterized by an atypical placement of a catalytic lysine within the kinase domain. Mutations in human WNK1 or WNK4 cause an autosomal dominant syndrome of hypertension and hyperkalemia, reflecting the fact that WNK kinases are critica...

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Detalhes bibliográficos
Publicado no:Curr Top Dev Biol
Main Authors: Rodan, Aylin R., Jenny, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5329892/
https://ncbi.nlm.nih.gov/pubmed/28236964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.ctdb.2016.08.004
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