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DC-Derived IL-10 Modulates Pro-inflammatory Cytokine Production and Promotes Induction of CD4(+)IL-10(+) Regulatory T Cells during Plasmodium yoelii Infection

The cytokine IL-10 plays a crucial role during malaria infection by counteracting the pro-inflammatory immune response. We and others demonstrated that Plasmodium yoelii infection results in enhanced IL-10 production in CD4(+) T cells accompanied by the induction of an immunosuppressive phenotype. H...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Loevenich, Katharina, Ueffing, Kristina, Abel, Simone, Hose, Matthias, Matuschewski, Kai, Westendorf, Astrid M., Buer, Jan, Hansen, Wiebke
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328999/
https://ncbi.nlm.nih.gov/pubmed/28293237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00152
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