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Absence of DJ-1 causes age-related retinal abnormalities in association with increased oxidative stress

Oxidative stress alters physiological function in most biological tissues and can lead to cell death. In the retina, oxidative stress initiates a cascade of events leading to focal loss of RPE and photoreceptors, which is thought to be a major contributing factor to geographic atrophy. Despite these...

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Publicado en:Free Radic Biol Med
Autores principales: Bonilha, Vera L., Bell, Brent A., Rayborn, Mary E., Samuels, Ivy S., King, Anna, Hollyfield, Joe G., Xie, Chengsong, Cai, Huaibin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328840/
https://ncbi.nlm.nih.gov/pubmed/28088625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.01.018
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