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Role and mechanism of action of Sclerostin in bone
After discovering that lack of Sost/sclerostin expression is the cause of the high bone mass human syndromes Van Buchem disease and sclerosteosis, extensive animal experimentation and clinical studies demonstrated that sclerostin plays a critical role in bone homeostasis and that its deficiency or p...
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| 發表在: | Bone |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5328835/ https://ncbi.nlm.nih.gov/pubmed/27742498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2016.10.007 |
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