Llwytho...

Application of anti-Sclerostin therapy in non-osteoporosis disease models

Sclerostin, a known inhibitor of the low density lipoprotein related protein 5 and 6 (LRP5 and LRP6) cell surface signaling receptors, is integral in the maintenance of normal bone mass and strength. Patients with loss of function mutations in SOST or missense mutations in LRP5 that prevent Sclerost...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bone
Prif Awdur: Jacobsen, Christina M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328800/
https://ncbi.nlm.nih.gov/pubmed/27780792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2016.10.018
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