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Application of anti-Sclerostin therapy in non-osteoporosis disease models

Sclerostin, a known inhibitor of the low density lipoprotein related protein 5 and 6 (LRP5 and LRP6) cell surface signaling receptors, is integral in the maintenance of normal bone mass and strength. Patients with loss of function mutations in SOST or missense mutations in LRP5 that prevent Sclerost...

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Bibliografische gegevens
Gepubliceerd in:Bone
Hoofdauteur: Jacobsen, Christina M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328800/
https://ncbi.nlm.nih.gov/pubmed/27780792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2016.10.018
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