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Oxidative stress, metabolomics profiling, and mechanism of local anesthetic induced cell death in yeast

The World Health Organization designates lidocaine as an essential medicine in healthcare, greatly increasing the probability of human exposure. Its use has been associated with ROS generation and neurotoxicity. Physiological and metabolomic alterations, and genetics leading to the clinically observ...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Boone, Cory H.T., Grove, Ryan A., Adamcova, Dana, Seravalli, Javier, Adamec, Jiri
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328717/
https://ncbi.nlm.nih.gov/pubmed/28236766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.01.025
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