NADPH oxidase-derived H(2)O(2) mediates the regulatory effects of microglia on astrogliosis in experimental models of Parkinson's disease

Astrogliosis has long been recognized in Parkinson's disease (PD), the most common neurodegenerative movement disorder. However, the mechanisms of how astroglia become activated remain unclear. Reciprocal interactions between microglia and astroglia play a pivotal role in regulating the activit...

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Veröffentlicht in:Redox Biol
Hauptverfasser: Hou, Liyan, Zhou, Xueying, Zhang, Cong, Wang, Ke, Liu, Xiaofang, Che, Yuning, Sun, Fuqiang, Li, Huihua, Wang, Qingshan, Zhang, Dan, Hong, Jau-Shyong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328707/
https://ncbi.nlm.nih.gov/pubmed/28237879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.02.016
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