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Nuclear Receptors Resolve Endoplasmic Reticulum Stress to Improve Hepatic Insulin Resistance
Chronic endoplasmic reticulum (ER) stress culminating in proteotoxicity contributes to the development of insulin resistance and progression to type 2 diabetes mellitus. Pharmacologic interventions targeting several different nuclear receptors have emerged as potential treatments for insulin resista...
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Publicado no: | Diabetes Metab J |
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Autor principal: | |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Korean Diabetes Association
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5328691/ https://ncbi.nlm.nih.gov/pubmed/28236381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4093/dmj.2017.41.1.10 |
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