Blocking iNOS and endoplasmic reticulum stress synergistically improves insulin resistance in mice

OBJECTIVE: Recent data show that iNOS has an essential role in ER stress in obesity. However, whether iNOS is sufficient to account for obesity-induced ER stress and Unfolded Protein Response (UPR) has not yet been investigated. In the present study, we used iNOS knockout mice to investigate whether...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Metab
Auteurs principaux: Zanotto, Tamires M., Quaresma, Paula G.F., Guadagnini, Dioze, Weissmann, Lais, Santos, Andressa C., Vecina, Juliana F., Calisto, Kelly, Santos, Andrey, Prada, Patrícia O., Saad, Mario J.A.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2016
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5279911/
https://ncbi.nlm.nih.gov/pubmed/28180062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.12.005
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