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Nanoparticle-mediated miR200-b delivery for the treatment of diabetic retinopathy

We recently reported that the Ins2(Akita) mouse is a good model for late-onset diabetic retinopathy. Here, we investigated the effect of miR200-b, a potential anti-angiogenic factor, on VEGF receptor 2 (VEGFR-2) expression and to determine the underlying angiogenic response in mouse endothelial cell...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Control Release
Hauptverfasser: Mitra, Rajendra Narayan, Nichols, Chance A., Guo, Junjing, Makkia, Rasha, Cooper, Mark J., Naash, Muna I., Han, Zongchao
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328608/
https://ncbi.nlm.nih.gov/pubmed/27297781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2016.06.020
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