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Obatoclax Inhibits Alphavirus Membrane Fusion by Neutralizing the Acidic Environment of Endocytic Compartments

As new pathogenic viruses continue to emerge, it is paramount to have intervention strategies that target a common denominator in these pathogens. The fusion of viral and cellular membranes during viral entry is one such process that is used by many pathogenic viruses, including chikungunya virus, W...

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Podrobná bibliografie
Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Varghese, Finny S., Rausalu, Kai, Hakanen, Marika, Saul, Sirle, Kümmerer, Beate M., Susi, Petri, Merits, Andres, Ahola, Tero
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328557/
https://ncbi.nlm.nih.gov/pubmed/27993855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02227-16
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