The Antiviral Alkaloid Berberine Reduces Chikungunya Virus-Induced Mitogen-Activated Protein Kinase Signaling

Chikungunya virus (CHIKV) has infected millions of people in the tropical and subtropical regions since its reemergence in the last decade. We recently identified the nontoxic plant alkaloid berberine as an antiviral substance against CHIKV in a high-throughput screen. Here, we show that berberine i...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Varghese, Finny S., Thaa, Bastian, Amrun, Siti Naqiah, Simarmata, Diane, Rausalu, Kai, Nyman, Tuula A., Merits, Andres, McInerney, Gerald M., Ng, Lisa F. P., Ahola, Tero
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068526/
https://ncbi.nlm.nih.gov/pubmed/27535052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01382-16
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