The Antiviral Alkaloid Berberine Reduces Chikungunya Virus-Induced Mitogen-Activated Protein Kinase Signaling

Chikungunya virus (CHIKV) has infected millions of people in the tropical and subtropical regions since its reemergence in the last decade. We recently identified the nontoxic plant alkaloid berberine as an antiviral substance against CHIKV in a high-throughput screen. Here, we show that berberine i...

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Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Varghese, Finny S., Thaa, Bastian, Amrun, Siti Naqiah, Simarmata, Diane, Rausalu, Kai, Nyman, Tuula A., Merits, Andres, McInerney, Gerald M., Ng, Lisa F. P., Ahola, Tero
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2016
Aiheet:
Vaccines and Antiviral Agents
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068526/
https://ncbi.nlm.nih.gov/pubmed/27535052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01382-16
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